N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

：纯度： CAS：

英文名称：N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

品牌：TRC

规格	目录价格	会员价格	数量
2.5mg	￥ ǿŦĩĒĴƺƺ	一般3-5周，以TRC实际库存为准	￥ ǿŦĩĒĴƺƺ	- +
5mg	￥ ŦōĒĊĴƺƺ	一般3-5周，以TRC实际库存为准	￥ ŦōĒĊĴƺƺ	- +
10mg	￥ üĒüƺĴƺƺ	一般3-5周，以TRC实际库存为准	￥ üĒüƺĴƺƺ	- +

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基本信息

英文名称

N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

分子式

C28 H43 F N3 O9 P Si

Smiles Code

纯度

Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;

N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-a-fluoro-b-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)

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质量 (g) = 浓度 (mol/L) × 体积 (L) × (g/mol)

质量			浓度			体积			*
		=			×			×

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N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

英文名称：N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

基本信息

英文名称

N-[[P(S),2'R]-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester

分子式

C28 H43 F N3 O9 P Si

Smiles Code

纯度

资源工具

摩尔计算器

常用工具

给我们留言

您有任何问题或者建议，欢迎给我们留言，我们将尽快答复您。 * 是必填项。