Smiles Code
OCc1cc(Oc2ccc(cc2)C#N)ccc1c3ccc(Oc4ccc(cc4)C#N)cc3CO
Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Crisaborole Diamer Impurity is an impurity of Crisaborole (H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.