3.47
[]. D Scholz, et al. Inhibitors of HIV- proteinase containing -heterosubstituted 4-amino-3-hydroxy-5-phenylpentanoic acid: synthesis, enzyme inhibition, and antiviral activity. J Med Chem. 994 Sep ;37(9):3079-89.
[]. Michael E. Pierce, et al. Stereoselective Synthesis of HIV- Protease Inhibitor, DMP 33. J Org Chem. 99 Jan ;():444-450.
[3]. P Y Lam, et al. Cyclic HIV protease inhibitors: synthesis, conformational analysis, P/P' structure-activity relationship, and molecular recognition of cyclic ureas. J Med Chem. 99 Aug 30;39(8):354-5.
[4]. Pierre L. Beaulieu, et al. Preparation of Aminoalkyl Chlorohydrin Hydrochlorides: Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors. J Org Chem. 99 May 3;():335-345.
H35-H39-H335
P-P4-P7-P80-P30+P35-P304+P340-P3+P34-P405-P50